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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253383Generated: October 30, 2026

Methanol → HCID 58086875, compound

https://huagongshe.com/reaction/253383

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant1H-Pyrrolo(2,3-b)pyridineHCID 9222—
ReactantPotassium HydroxideHCID 14797—
Reactant4-(Benzyloxy)-3-methoxybenzaldehydeHCID 75506—
ProductHCID 58086875HCID 58086875—

Reaction Steps

Methanol (125 mL) and potassium hydroxide (4.4 g, 79 mmol) were mixed with 1H-pyrrolo[2,3-b]pyridine (6, 3.1 g, 26.6 mmol) and 4-benzyloxy-3-methoxy-benzaldehyde (33, 12.9 g, 53.2 mmol). The reaction was stirred at room temperature for 2 days. The resulting white solid was filtered and washed with water, Crude material was carried forward without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872018B2
Source datasetuspto-grants-2011_01
ORD IDord-295644fbaae142f1bbc017ff27f391f3
Source noteuspto-grants-2011_01