1H-Pyrrolo(2,3-b)pyridine → HCID 178526243, compound

HRID 253422Notes

Reaction equation

HRID 253422 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1.C1C=C(Cl)C=C(C(OO)=[O:18])C=1>C(COC)OC>[NH:1]1[C:9]2=[N+:8]([O-:18])[CH:7]=[CH:6][CH:5]=[C:4]2[CH:3]=[CH:2]1

Participants

4

Reactant 2

HCID 92221H-Pyrrolo(2,3-b)pyridineHCID 70297m-Chloroperbenzoic acid

Product 1

HCID 178526243HCID 178526243, compound

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

1H-Pyrrolo[2,3-b]pyridine 7-oxide 91 was synthesized by reacting 7-azaindole 6 with an oxidizing agent (e.g. m-CPBA) in a non-reactive solvent (e.g. dimethoxyethane) as described by Schneller, S. W.; Luo, Jiann-Kuan. J. Org. Chem. 1980, 45:4045-4048. The compound was isolated by filtration of the resulting solid that forms upon standing at 5° C. for typically 1-3 h.

Workup

  1. customThe compound was isolated by filtration of the resulting solid that

Sources & evidence

ORD record
ord-9ea56ead990241ee934f7fe858cb78fd
Source dataset
uspto-grants-2011_01
Patent number
US07872018B2

Reaction notes

Loading…