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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253900Generated: October 26, 2026

Dithioerythritol → 1-(1-Acetyl-piperidin-4-yl)-3-[5-(2-azepan-1-yl-ethylsulfanyl)-thiazol-2-yl]-1-cyclohexyl urea

https://huagongshe.com/reaction/253900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDithioerythritolHCID 439352—
Reactant2-(Hexamethyleneimino)ethyl chlorideHCID 53445278—
Reactant1-(1-Acetyl-piperidin-4-yl)-1-cyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-ureaHCID 86611190—
Product1-(1-Acetyl-piperidin-4-yl)-3-[5-(2-azepan-1-yl-ethylsulfanyl)-thiazol-2-yl]-1-cyclohexyl ureaHCID 57883731—

Reaction Steps

Prepared as described in general procedures (H) and (I) using 1-(1-acetyl-piperidin-4-yl)-1-cyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 2-(hexamethyleneimino)ethylchloride

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-8b484f7758bd48feadaaca6b3416cb56
Source noteuspto-grants-2011_01