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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254283Generated: October 30, 2026

HCID 59321321, compound → HCID 66862726, compound

https://huagongshe.com/reaction/254283

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59321321HCID 59321321—
ReactantHCID 178418361HCID 178418361—
CatalystNickelHCID 935—
SolventEthanolHCID 702—
ProductHCID 66862726HCID 66862726—

Reaction Conditions

Temperature42.5 °C

Reaction Steps

3.03 g 2-(2-Cyclohexyl-4-methyl-imidazol-1-yl)-4-fluoro-nitrobenzene (10 mmol) were dissolved in 50 ml ethanol, 0.5 g Raney-Nickel was added and the mixture was heated 5 hours in a closed vessel at 40-45° C. and 10 bar hydrogen. After cooling the catalyst was removed and the filtrate was distilled to dryness.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875618B2
Source datasetuspto-grants-2011_01
ORD IDord-c2a018849c254c529a67ca4bec83e17d
Source noteuspto-grants-2011_01