Potassium Carbonate → HCID 42629709, compound

HRID 254313Notes

Reaction equation

HRID 254313 reaction equation
C[O:2][C:3]1[CH:12]=[C:11]([O:13]C)[CH:10]=[C:9]2[C:4]=1[N:5]=[C:6]([CH3:26])[C:7]1[N:8]2[C:15]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=2[CH3:25])=[N:16][C:17]=1[CH3:18].B(Br)(Br)Br.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[OH:2][C:3]1[CH:12]=[C:11]([OH:13])[CH:10]=[C:9]2[C:4]=1[N:5]=[C:6]([CH3:26])[C:7]1[N:8]2[C:15]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=2[CH3:25])=[N:16][C:17]=1[CH3:18]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 25134Boron tribromideHCID 42629707HCID 42629707, compound

Product 1

HCID 42629709HCID 42629709, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

0.3 g 6,8-Dimethoxy-3,4-dimethyl-1-(2-methylphenyl)-imidazo[1,5-a]quinoxaline, 30 mL dichloromethane and 5 mL BBr3 were heated in a closed vessel for 3 hours at 130° C. After cooling the suspension was given in 250 mL ice-cooled aqueous potassium carbonate solution. After stirring for 30 min at pH 7-9 the precipitate was filtered off, washed with water and purified with silica gel, dichloromethane/methanol 9/1.

Workup

  1. temperatureAfter cooling the suspension
  2. filtrationwas filtered off
  3. washwashed with water
  4. custompurified with silica gel, dichloromethane/methanol 9/1

Sources & evidence

ORD record
ord-3b0bd6f828514bad8e2d1822a7f83f7c
Source dataset
uspto-grants-2011_01
Patent number
US07875618B2

Reaction notes

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