Potassium Carbonate → HCID 42629710, compound

HRID 254314Notes

Reaction equation

HRID 254314 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:12]2[C:13]3[C:18]([N:19]=[C:20]([CH3:21])[C:11]2=[C:10]([CH3:24])[N:9]=1)=[CH:17][C:16]([O:22]C)=[CH:15][CH:14]=3.B(Br)(Br)Br.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[N:12]2[C:13]3[C:18]([N:19]=[C:20]([CH3:21])[C:11]2=[C:10]([CH3:24])[N:9]=1)=[CH:17][C:16]([OH:22])=[CH:15][CH:14]=3

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 25134Boron tribromideHCID 42629591HCID 42629591, compound

Product 1

HCID 42629710HCID 42629710, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

5 g 1-(2-Chlorophenyl)-3,4-dimethyl-7-methoxy-imidazo(1,5-a)quinoxaline, 100 mL dichloromethane and 12 mL BBr3 were heated in a closed vessel for 3 hours at 110° C. After cooling the suspension was given in 600 mL ice-cooled aqueous potassium carbonate solution. After stirring for 30 min at pH 7-9 the precipitate was filtered off, washed with water and dried.

Workup

  1. temperatureAfter cooling the suspension
  2. filtrationwas filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-5470d91d4be04c3b9a2241467eddd17d
Source dataset
uspto-grants-2011_01
Patent number
US07875618B2

Reaction notes

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