反应详情

1 g 1-(2-Chloro-phenyl)-3,4-dimethyl-7-hydroxy-imidazo(1,5-a)quinoxaline, 2.24 g Caesium carbonate, 50 mL N,N-dimethylformamide, 6 mL water, and 0.86 g 2-Chloro-methylquinoline hydrochloride were stirred for 3 h at 130° C. The reaction mixture was given into 150 mL water, filtered off, washed with water, dried under reduced pressure, and purified with silica gel, dichloromethane/methanol=95/5.

1. filtrationfiltered off
2. washwashed with water
3. customdried under reduced pressure
4. custompurified with silica gel, dichloromethane/methanol=95/5