反应详情

温度

40 °C

2.0 g 1-(2-Chlorophenyl)-3,4-dimethyl-7-(3-nitrobenzyloxy)-imidazo(1,5-a)quinoxaline was dissolved in 50 mL methanol, 0.4 g Raney Nickel was added followed by dropwise addition of 2.1 mL hydrazine hydrate. The reaction mixture was stirred 1 h at 40° C. and 10 min at reflux. After cooling the catalyst was filtered off, the solvent was removed by distillation and the residue was re-crystallised from 2-propanol.

1. temperatureat reflux
2. temperatureAfter cooling the catalyst
3. filtrationwas filtered off
4. customthe solvent was removed by distillation
5. customthe residue was re-crystallised from 2-propanol