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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254478Generated: October 31, 2026

Ethylenediamine → 2-(2,6-Bis-trifluoromethyl-benzyl)-4,5-dihydro-1H-imidazole

https://huagongshe.com/reaction/254478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-(2,6-Bis(trifluoromethyl)phenyl)acetonitrileHCID 58951838—
Product2-(2,6-Bis-trifluoromethyl-benzyl)-4,5-dihydro-1H-imidazoleHCID 58951676—

Reaction Steps

2-(2,6-Bis-trifluoromethyl-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2,6-bis-trifluoromethyl-phenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): colourless crystals; MS (EI): 296.2 (M+.), 275.1 ((M-F)+.), 267.1 ((M-C2H5)+.), 227.1 (((M-imidazoline)+.), 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-9bc0b26fa98a4dd7b8d3095a5da5931d
Source noteuspto-grants-2011_01