Trimethylsilyl cyanide → HCID 58951694, compound

HRID 254484Notes

Reaction equation

HRID 254484 reaction equation
Br[CH:2]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[CH:6]=1)[CH2:3][CH3:4].C[Si]([C:16]#[N:17])(C)C>>[Cl:11][C:7]1[CH:6]=[C:5]([CH:2]([CH2:3][CH3:4])[C:16]#[N:17])[CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 82115Trimethylsilyl cyanideHCID 22987705HCID 22987705, compound

Product 1

HCID 58951694HCID 58951694, compound

Procedure

rac-2-(3-chloro-phenyl)-butyronitrile was prepared from rac-1-(1-bromo-propyl)-3-chloro-benzene and trimethylsilyl cyanide in analogy to Example 23 c): colourless oil.

Sources & evidence

ORD record
ord-6ff114b4d43d4ecdac2dbdff7f3377db
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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