Ethylenediamine → Hydrochloric Acid

HRID 254501Notes

Reaction equation

HRID 254501 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][C:10]#[N:11].[CH2:12](N)[CH2:13][NH2:14]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][C:10]1[NH:14][CH2:13][CH2:12][N:11]=1.[ClH:1]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 1235752-Chloro-6-fluorophenylacetonitrile

Product 2

HCID 313Hydrochloric AcidHCID 58951774HCID 58951774, compound

Procedure

2-(2-Chloro-6-fluoro-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-chloro-6-fluoro-phenyl)-acetonitrile and ethylene diamine in analogy to Example 22; isolated as hydrochloride: colourless powder; MS (ISP): 212.9 ((M+H)+.).

Sources & evidence

ORD record
ord-4dd7516599974ca1b8e96717d7b80c36
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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