Ethylenediamine → 2-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazole

HRID 254507Notes

Reaction equation

HRID 254507 reaction equation
[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][C:11]#[N:12].[CH2:15](N)[CH2:16][NH2:17]>>[F:1][C:2]([F:13])([F:14])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][C:11]1[NH:17][CH2:16][CH2:15][N:12]=1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 27773212-(Trifluoromethoxy)phenylacetonitrile

Product 1

HCID 589517512-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazole

Procedure

2-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-trifluoromethoxy-phenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): yellow powder; MS (ISP): 245.0 ((M+H)+.).

Sources & evidence

ORD record
ord-6001fe8fc7bf483686b87d98a170569c
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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