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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254507Generated: November 1, 2026

Ethylenediamine → 2-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazole

https://huagongshe.com/reaction/254507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-(Trifluoromethoxy)phenylacetonitrileHCID 2777321—
Product2-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazoleHCID 58951751—

Reaction Steps

2-(2-Trifluoromethoxy-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-trifluoromethoxy-phenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): yellow powder; MS (ISP): 245.0 ((M+H)+.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-6001fe8fc7bf483686b87d98a170569c
Source noteuspto-grants-2011_01