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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254573Generated: October 30, 2026

Ethylenediamine → 2-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazole

https://huagongshe.com/reaction/254573

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-(2,2-Dibromo-vinyl)-3-ethyl-1,4-difluoro-benzeneHCID 58951856—
Product2-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazoleHCID 58951748—

Reaction Steps

2-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazole was prepared from 2-(2,2-dibromo-vinyl)-3-ethyl-1,4-difluoro-benzene and ethylenediamine in analogy to Example 1e): yellow crystals; MS (ISP): 225.3 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-d31e599ce3fe4b8a9de51e3c0168bd59
Source noteuspto-grants-2011_01