p-Toluenesulfonic acid → HCID 178448988, compound

HRID 254579Notes

Reaction equation

HRID 254579 reaction equation
[F:1][C:2]1[C:9]([O:10][CH3:11])=[CH:8][CH:7]=[C:6]([F:12])[C:3]=1[CH:4]=O.[CH2:13]([NH2:17])[CH2:14][CH2:15][CH3:16].C1(C)C=CC(S(O)(=O)=O)=CC=1>>[CH2:13](/[N:17]=[CH:4]/[C:3]1[C:6]([F:12])=[CH:7][CH:8]=[C:9]([O:10][CH3:11])[C:2]=1[F:1])[CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 6101p-Toluenesulfonic acidHCID 8007ButylamineHCID 5990732,6-Difluoro-3-methoxybenzaldehyde

Product 1

HCID 178448988HCID 178448988, compound

Procedure

Butyl-[1-(2,6-difluoro-3-methoxy-phenyl)-meth-(E)-ylidene]-amine was prepared from 2,6-difluoro-3-methoxybenzaldehyde, N-butylamine and p-toluenesulphonic acid in analogy to Example 186a): red oil; MS (ISP): 228.4 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-837e7a3fddea4469af4ebb639165dcd0
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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