Benzyl Bromide → HCID 58951803, compound

HRID 254597Notes

Reaction equation

HRID 254597 reaction equation
[CH2:1]([C:3]1[C:10]([OH:11])=[CH:9][CH:8]=[C:7]([CH2:12][CH3:13])[C:4]=1[CH:5]=[O:6])[CH3:2].C(=O)([O-])[O-].[Cs+].[Cs+].[CH2:20](Br)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:20]([O:11][C:10]1[C:3]([CH2:1][CH3:2])=[C:4]([C:7]([CH2:12][CH3:13])=[CH:8][CH:9]=1)[CH:5]=[O:6])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 10796Cesium carbonateHCID 58951851HCID 58951851, compound

Product 1

HCID 58951803HCID 58951803, compound

Procedure

3-Benzyloxy-2,6-diethyl-benzaldehyde was prepared from 2,6-diethyl-3-hydroxy-benzaldehyde, cesium carbonate and benzyl bromide in analogy to Example 213b): yellow oil; 1H-NMR (CDCl3): 1.20 (3H, t, CH3), 1.21 (3H, t, CH3), 2.87 (2H, q, CH2), 3.03 (2H, q, CH2), 5.09 (2H, s, OCH2), 7.04 (2H, ABq, 2×ArH), 7.33-7.45 (5H, m, Ph), 10.58 (1H, s, CH═O).

Sources & evidence

ORD record
ord-2313567c11dc481c987545d31de13987
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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