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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254605Generated: October 31, 2026

Trifluoroacetic acid → HCID 58951740, compound

https://huagongshe.com/reaction/254605

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylsilaneHCID 12052—
ReactantHCID 58951705HCID 58951705—
ProductHCID 58951740HCID 58951740—

Reaction Steps

4-[3-(1H-Imidazol-2-ylmethyl)-phenyl]-pyridine was prepared from rac-(1H-imidazol-2-yl)-(3-pyridin-4-yl-phenyl)-methanol, triethylsilane and trifluoroacetic acid in analogy to Example 191e): white crystals; MS (ISP): 236.1 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-77ee5b67ddff482cab57aa797c9c4a81
Source noteuspto-grants-2011_01