Iodine → HCID 66851637, compound

HRID 254680Notes

Reaction equation

[O:1]1[CH2:6][CH2:5][C:4](=O)[CH2:3][CH2:2]1.[CH3:8][CH:9]([CH3:12])[CH2:10][NH2:11].[S-:13][C:14]#[N:15].[K+].II>>[CH2:10]([N:11]1[C:4]2[CH2:3][CH2:2][O:1][CH2:6][C:5]=2[S:13][C:14]1=[NH:15])[CH:9]([CH3:12])[CH3:8]

Participants

Reactant 4

HCID 807Iodine

HCID 6558Isobutylamine

HCID 121599Tetrahydro-4H-pyran-4-one

HCID 516872Potassium thiocyanate

Product 1

HCID 66851637HCID 66851637, compound

Procedure

Commercially available dihydro-2H-pyran-4(3H)-one (Aldrich), 2-methylpropan-1-amine (Aldrich), potassium thiocyanate (Aldrich) and iodine (EMD chemicals) were processed using the method described in Example 91A to afford the title compound. MS (ESI+) m/z 213 (M+H)+.

Sources & evidence

ORD record: ord-fce028d2a9f643518e54fe88d131a9a9
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07875640B2

Reaction notes

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