2-Bromoethyl methyl ether → 6-Fluoro-3-(2-methoxyethyl)-3H-benzothiazol-2-ylideneamine hydrobromide

HRID 255072Notes

Reaction equation

HRID 255072 reaction equation
[F:1][C:2]1[CH:11]=[CH:10][C:5]2[N:6]=[C:7]([NH2:9])[S:8][C:4]=2[CH:3]=1.[CH3:12][O:13][CH2:14][CH2:15][Br:16]>>[BrH:16].[F:1][C:2]1[CH:11]=[CH:10][C:5]2[N:6]([CH2:15][CH2:14][O:13][CH3:12])[C:7](=[NH:9])[S:8][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 3199542-Amino-6-fluorobenzothiazole

Product 1

HCID 686235486-Fluoro-3-(2-methoxyethyl)-3H-benzothiazol-2-ylideneamine hydrobromide

Procedure

Commercially available 6-fluoro-benzothiazol-2-ylamine and 2-bromoethyl methyl ether were processed as described for Example 2A to afford the title compound MS (ESI+) m/z 227 (M+H)+.

Sources & evidence

ORD record
ord-e20ffc8313b240d2bd38875d07555e88
Source dataset
uspto-grants-2011_01
Patent number
US07875639B2

Reaction notes

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