2-Bromoethyl methyl ether → 5-Fluoro-3-(2-methoxyethyl)-3H-benzothiazol-2-ylideneamine

HRID 255074Notes

Reaction equation

HRID 255074 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([NH2:10])=[N:7][C:6]=2[CH:11]=1.[CH3:12][O:13][CH2:14][CH2:15]Br>>[F:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8](=[NH:10])[N:7]([CH2:15][CH2:14][O:13][CH3:12])[C:6]=2[CH:11]=1

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 8212032-Amino-5-fluorobenzothiazole

Product 1

HCID 668586895-Fluoro-3-(2-methoxyethyl)-3H-benzothiazol-2-ylideneamine

Procedure

Commercially available 5-fluoro-benzothiazol-2-ylamine and 2-bromoethyl methyl ether were processed as described for Example 46A to afford the title compound. MS (ESI+) m/z 227 (M+H)+.

Sources & evidence

ORD record
ord-5a8d92b3617b4b95ae2c52127a9d3f11
Source dataset
uspto-grants-2011_01
Patent number
US07875639B2

Reaction notes

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