2-Bromoethanol → HCID 66858594, compound

Participants

Reaction Steps

A mixture of 4,5-dimethlyl-thiazol-2-ylamine (1.0 g, 7.8 mmol) and 2-bromoethanol (0.68 mL, 9.4 mmol) were processed as described in Example 8A to provide 0.92 g (47%) of the title compound 1H NMR (DMSO-d6, 300 MHz) δ ppm 2.19 (s, 6 H), 3.61-3.68 (m, 2 H), 4.03 (t, J=4.9 Hz, 2 H), 5.14 (brs, 1H) 9.27 (s, 1 H); MS (DCI/NH3) m/z 173 (M+H)+.

Provenance & Evidence