2-Bromoethyl methyl ether → 5-Tert-butyl-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

HRID 255124Notes

Reaction equation

HRID 255124 reaction equation
[C:1]([C:5]1[S:9][C:8]([NH2:10])=[N:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:11][O:12][CH2:13][CH2:14][Br:15]>>[BrH:15].[C:1]([C:5]1[S:9][C:8](=[NH:10])[N:7]([CH2:14][CH2:13][O:12][CH3:11])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 6764855-tert-Butyl-1,3-thiazol-2-amine

Product 1

HCID 668591825-Tert-butyl-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

Procedure

A mixture of Example 136A and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 215 (M+H)+.

Sources & evidence

ORD record
ord-6bae0336ba4e40509b106ce78b528d9d
Source dataset
uspto-grants-2011_01
Patent number
US07875639B2

Reaction notes

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