反应详情

温度

50 °C

The product from Example 1 (0.119 g, 0.5 mmol) and the product from Example 23, Step A (0.157 g, 0.54 mmol) were combined in tetrahydrofuran (8 mL), briefly heated to 50° C., and then allowed to stand for 6 hours at room temperature. The reaction mixture was concentrated to dryness and the residue triturated with hexanes/ethyl acetate. The product was collected by filtration (0.14 g), mp softening at 120° C., gradual decomposition.

1. concentrationThe reaction mixture was concentrated to dryness
2. customthe residue triturated with hexanes/ethyl acetate
3. filtrationThe product was collected by filtration (0.14 g), mp softening at 120° C.