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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255145Generated: October 30, 2026

2-Bromoethyl methyl ether → 5-(4,4-Difluorocyclohexyl)-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

https://huagongshe.com/reaction/255145

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoethyl methyl etherHCID 80972—
ReactantHCID 66859799HCID 66859799—
Product5-(4,4-Difluorocyclohexyl)-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromideHCID 66859539—

Reaction Steps

A mixture of Example 184E and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 277 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875639B2
Source datasetuspto-grants-2011_01
ORD IDord-ef9079e2135f48609f982b9d3b7bbcc7
Source noteuspto-grants-2011_01