HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetyl bromide → 6-Bromo-2H-1,4-benzoxazin-3(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetyl bromide | HCID 61147 | — |
| Reactant | 2-Amino-4-Bromophenol | HCID 351840 | — |
| Reactant | 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonitrile | HCID 10654813 | — |
| Product | 6-Bromo-2H-1,4-benzoxazin-3(4H)-one | HCID 16218142 | — |
Reaction Steps
2-Amino-4-bromophenol (2.1 g, 11 mmol) and bromo acetyl bromide (1.4 mL, 16.5 mmol) were reacted according to the procedure for Intermediate 60 to afford product as a solid, 2.1 g (85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07875715B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-a2dc38e975854372b97e525698825ee0 |
| Source note | uspto-grants-2011_01 |