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HRID255248

反应详情

EQUATION

反应方程式

HRID 255248 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc2c(c1)NC(=O)CO2
HCID13204952

6-Methoxy-2H-1,4-benzoxazin-3(4H)-one

C9H9NO3

结构：CCOC(=O)COc1ccc(C(C)=O)cc1[N+](=O)[O-]
HCID86642623

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CC(=O)c1ccc2c(c1)NC(=O)CO2
HCID3641956

6-Acetyl-2H-1,4-benzoxazin-3(4H)-one

C10H9NO3

收率 51%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Fe]
催化剂HCID23925

Iron

Fe

结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

Ethyl (4-acetyl-2-nitrophenoxy)acetate (Intermediate 90) was reacted with iron in acetic acid as described for Intermediate 48. The crude product was obtained as an off white solid after work up. Recrystallization with ethyl acetate/methanol afforded the product as a colorless solid in 51% yield.

WORKUP

后处理

  1. customThe crude product was obtained as an off white solid after work up
  2. customRecrystallization with ethyl acetate/methanol