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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255258Generated: October 29, 2026

1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrile → HCID 66775065, compound

https://huagongshe.com/reaction/255258

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(4-Aminopiperidin-1-yl)ethyl]-2-oxo-1,2-dihydroquinoline-7-carbonitrileHCID 60200920—
ReactantHCID 86642628HCID 86642628—
ProductHCID 66775065HCID 66775065—

Reaction Steps

tert-Butyl {1-[2-(3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]piperidin-4-yl}carbamate (Intermediate 98) was reacted as described for Intermediate 14. The crude trifluoro acetate of the title compound was obtained as a colorless solid and used without further purification for the next step (quantitative yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875715B2
Source datasetuspto-grants-2011_01
ORD IDord-eecdf36444d04f5abd054c147683dc4f
Source noteuspto-grants-2011_01