Acetic Anhydride → HCID 178492024, compound

Participants

Reaction Steps

Using the method of Example 133, 1-(4-methoxyphenyl)-1H-imidazo[4,5-c]quinolin-5-oxide (from Exmaple 86) was reacted with acetic anhydride to provide 4-hydroxy-1-(4-methoxyphenyl)-1H-imidazo[4,5-c]quinoline m.p. >300° C. after recrystallization from N,N-dimethylformamide. Analysis: Calculated for C17H13N3O2 : %C, 70.1; %H, 4.5; %N, 14.4; Found: %C, 70.0; %H, 4.4; %N, 14.5.

Provenance & Evidence