Formic Acid → HCID 13958443, compound

Participants

Reaction Steps

Using the method of Example 137, 3-amino-6-fluoro-2-methyl-4-methylaminoquinoline (from example 44) was reacted with formic acid to provide 1,4-dimethyl-8-fluoro-1H-imidazo[4,5-c]quinoline, m.p. 184°-186° C. Analysis: Calculated for C12H10FN3 : %C, 67.0; %H, 4.7; %N, 19.5; Found: %C, 66.6; %H, 4.4; %N, 19.7.

Provenance & Evidence