Benzyl Chloride → HCID 13958468, compound

HRID 255548Notes

Reaction equation

HRID 255548 reaction equation
[SH:1][C:2]1[N:3]([CH3:15])[C:4]2[C:13]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=[CH:6][C:5]=2[N:14]=1.[CH2:16](Cl)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([S:1][C:2]1[N:3]([CH3:15])[C:4]2[C:13]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=[CH:6][C:5]=2[N:14]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 7503Benzyl ChlorideHCID 178481669HCID 178481669, compound

Product 1

HCID 13958468HCID 13958468, compound

Procedure

Using the method of Example 162, 2-mercapto-1-methyl-1H-imidazo[4,5-c]quinoline (from Example 165 below) was reacted with benzyl chloride to provide 2-benzylthio-1-methyl-1H-imidazo[4,5-c]quinoline. Recrystallization first from isopropanol then from ethanol provided solid product, m.p. 160°-163° C. Analysis: Calculated for C18H15N3S: %C, 70.8; %H, 5.0; %N, 13.8. Found: %C, 70.3; %H, 4.7; %N, 13.7.

Sources & evidence

ORD record
ord-7e1656056d4c4c03918023d41a28d4db
Source dataset
uspto-grants-1987_10
Patent number
US04698348

Reaction notes

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