HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-Acetyl-N-(1,2-benzothiazol-3-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1,2-Benzisothiazol-3-amine | HCID 89966 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Product | N-Acetyl-N-(1,2-benzothiazol-3-yl)acetamide | HCID 20183861 | — |
Reaction Steps
A mixture consisting of 11.7 g of 3-aminobenzisothiazole, 126 ml of acetanhydride and 0.2 g of sodium acetate is stirred for 48 hours at 100°-110? C. After concentration by evaporation and then chromatography (silica gel; eluant: hexane/diethyl ether 2:1), the product is recrystallised from hexane/diethyl ether to thus obtain the compound No. 1 of the formula ##STR10## having a melting point of 65°-67° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04698358 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-4f12d824005b4699839a36eb2fc37f47 |
| Source note | uspto-grants-1987_10 |