反应详情

A solution of N-(2-dimethylaminoethyl)-6-methyl-4-(3-nitrophenyl)-2-phenyl-5-pyrimidinecarboxamide (1 g) and methyl iodide (10.46 ml) in ethyl acetate (2 ml) was stirred for 5 days at room temperature. The reaction mixture was evaporated and the residue was recrystallized from ethyl alcohol to afford N-(2-trimethylammonioethyl)-6-methyl-4-(3-nitrophenyl)-2-phenyl-5-pyrimidinecarboxamide iodide (0.95 g).

1. customThe reaction mixture was evaporated
2. customthe residue was recrystallized from ethyl alcohol