Hydrazine hydrate (1:1) → HCID 178526520, compound

HRID 255895Notes

Reaction equation

HRID 255895 reaction equation
C[N:2](/[CH:4]=[CH:5]/[C:6]([C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][CH:9]=1)=O)C.O.[NH2:18]N>C(O)C>[N+:14]([C:11]1[CH:12]=[CH:13][C:8]([C:6]2[CH:5]=[CH:4][NH:2][N:18]=2)=[CH:9][CH:10]=1)([O-:16])=[O:15]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 1475992HCID 1475992, compound

Product 1

HCID 178526520HCID 178526520, compoundYield 78.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 1-(4-nitrophenyl)-3-N,N-dimethylamino-2-propen-1-one (27.3 g) and 85% hydrazine hydrate (23.6 g) in ethanol was heated at 60° C. for one hour. The crystallized solid was filtered to give 18.5 g of 3-(4-nitrophenyl)-pyrazole; M.p. 196°-197° C.

Workup

  1. filtrationThe crystallized solid was filtered

Sources & evidence

ORD record
ord-e9caf5c197834ce287ee5e62ac9971e3
Source dataset
uspto-grants-1987_10
Patent number
US04699915

Reaction notes

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