Methyl iodide → HCID 13362251, compound

HRID 255913Notes

Reaction equation

[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1[CH:10]1[CH2:14][NH:13][C:12](=[O:15])[CH2:11]1.[H-].[Na+].[CH3:18]I>>[CH3:18][N:13]1[CH2:14][CH:10]([C:2]2[O:1][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[CH:3]=2)[CH2:11][C:12]1=[O:15]

Participants

Reactant 3

HCID 6328Methyl iodide

HCID 24758Sodium hydride

HCID 132452104-(1-Benzofuran-2-yl)pyrrolidin-2-one

Product 1

HCID 13362251HCID 13362251, compoundYield 81%

Procedure

The compound is prepared from 4-(2-benzofuryl)-pyrrolidin-2-one, sodium hydride and methyl iodide, as described in Example 5. B.p.(0.3 mm Hg)=172° C. M.p. 73° C. Yield: 81%.

Workup

custom(0.3 mm Hg)=172° C

Sources & evidence

ORD record: ord-3359f13f99254f7cb07549dad3101205
Source dataset: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04699918

Reaction notes

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