反应详情

A solution of 2,3-dichloro-4-(3-chloropropionyl)phenol (8.4 g, 0.033 mole) in methanol (30 ml) and potassium acetate (3.5 g, 0.033 mole) in methanol (30 ml) were united and refluxed for 20 minutes. The mixture was treated with chloroform (200 ml), washed with water, dried over MgSO4, filtered and the solvent removed from the filtrate by evaporation in vacuo. The residue was recrystallized from carbon tetrachloride to give 6 g of 2,3-dichloro-4-acryloylphenol, m.p. 135°-137° C.

1. temperaturerefluxed for 20 minutes
2. washwashed with water
3. dry with materialdried over MgSO4
4. filtrationfiltered
5. customthe solvent removed from the filtrate by evaporation in vacuo
6. customThe residue was recrystallized from carbon tetrachloride