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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255951Generated: November 2, 2026

2-Amino-4-methylpyridine → 4-Methyl-2-phthalimidopyridine

https://huagongshe.com/reaction/255951

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-methylpyridineHCID 1533—
ReactantPhthalic AnhydrideHCID 6811—
Reactant4-(Trichloromethyl)pyridin-2-amineHCID 13710117—
Product4-Methyl-2-phthalimidopyridineHCID 10999049—

Reaction Steps

A process for the preparation of 2-amino-4-trichloromethylpyridine of the formula I, wherein 2-amino-4-picoline is reacted with phthalic anhydride to give 4-methyl-2-phthalimidopyridine, the latter is chlorinated and the product is hydrolyzed.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04699983
Source datasetuspto-grants-1987_10
ORD IDord-109dcc2773f8420f9acc4994d6793d4d
Source noteuspto-grants-1987_10