HRID256029

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)CN1CC(c2ccccc2)SCC(NC(CCc2ccccc2)C(=O)OCc2ccccc2)C1=O

HCID20164783

未命名化合物

PRODUCTS

生成物

结构：O=C(O)CN1CC(c2ccccc2)SCC(NC(CCc2ccccc2)C(=O)OCc2ccccc2)C1=O

HCID20164782

未命名化合物

PROCEDURE

实验过程

0.10 g of isomer B of t-butyl α-[6-(1-benzyloxycarbonyl-3-phenylpropylamino)-5-oxo-2-phenylperhydro-1,4-thiazepin-4-yl]acetate (prepared as described in Example 21) was treated with trifluoroacetic acid to remove its t-butyl group by the process described in Example 3. 70 mg of the title compound were obtained as amorphous solid.

WORKUP

后处理

customto remove its t-butyl group by the process

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8c19cee1d5334ba3b06ae69c219ab119
来源数据集: uspto-grants-1987_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04699905
来源说明: uspto-grants-1987_10

反应 SMILES

[CH2:1]([O:8][C:9]([CH:11]([NH:20][CH:21]1[CH2:27][S:26][CH:25]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:24][N:23]([CH2:34][C:35]([O:37]C(C)(C)C)=[O:36])[C:22]1=[O:42])[CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.FC(F)(F)C(O)=O>>[CH2:1]([O:8][C:9]([CH:11]([NH:20][CH:21]1[CH2:27][S:26][CH:25]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:24][N:23]([CH2:34][C:35]([OH:37])=[O:36])[C:22]1=[O:42])[CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1