HRID256035

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CSC[C@@H](C(C)C)N(CC(=O)OC(C)(C)C)C1=O

HCID18610542

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CSC[C@@H](C(C)C)N(CC(=O)O)C1=O

HCID18610525

未命名化合物

收率 91.7%

PROCEDURE

实验过程

0.32 g of t-butyl α-{6(R)-[1(S)-ethoxycarbonyl-3-phenylpropylamino]-3(R)-isopropyl-5-oxoperhydro-1,4-thiazepin-4-yl}acetate (isomer B) synthesized as described in Example 27 was subjected to de-t-butylation with trifluoroacetic acid in the same manner as described in Example 3, to give 260 mg of the title compound as an amorphous solid.