HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | N-Boc-2-amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene | HCID 70445521 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 2-Amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene | HCID 56622469 | — |
Reaction Steps
N-Boc-2-amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene is dissolved in trifluoroacetic acid and the solution is stirred overnight. Water is added and the mixture made basic with 20% KOH. The mixture is extracted with ether, the organic layer dried over NaSO4 and evaporated to yield 2-amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04701552 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-78a1fce67f2f4ce4803fd36e39c80c5d |
| Source note | uspto-grants-1987_10 |