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HRID256253

反应详情

EQUATION

反应方程式

HRID 256253 的结构方程式

REACTANTS

反应物

3
结构：O
HCID962

Water

H2O

结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：CC(C)(C=CC1C(C)(C)CCC1(C)C)NC(=O)OC(C)(C)C
HCID70445521

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(N)C=CC1C(C)(C)CCC1(C)C
HCID56622469

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(O)C(F)(F)F
溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

N-Boc-2-amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene is dissolved in trifluoroacetic acid and the solution is stirred overnight. Water is added and the mixture made basic with 20% KOH. The mixture is extracted with ether, the organic layer dried over NaSO4 and evaporated to yield 2-amino-2-methyl-4-(2,2,5,5-tetramethyl-1-cyclopentyl)butene.

WORKUP

后处理

  1. extractionThe mixture is extracted with ether
  2. dry with materialthe organic layer dried over NaSO4
  3. customevaporated