反应详情

A 12.66 g portion of the BzMePhe was dissolved in 120 ml of acetic acid and 47 ml of HCl, and the solution was subjected to hydrogen catalytic reduction (room temperature, 8 hours) with addition of 5.0 g of 10% palladium-carbon catalyst. After separating off the catalyst by filtration, the filtrate was concentrated in vacuo, and the concentrate was recrystallized from ethanol (50 ml)-ether (500 ml) to give 7.93 g of MePhe, yeild 94.1%. M.p. 225° C.

1. customAfter separating off the catalyst
2. filtrationby filtration
3. concentrationthe filtrate was concentrated in vacuo
4. customthe concentrate was recrystallized from ethanol (50 ml)-ether (500 ml)