Benzyloxycarbonylglycine → HCID 20163746, compound

HRID 256369Notes

Reaction equation

HRID 256369 reaction equation
[CH2:1]([O:8][C:9]([NH:11][CH2:12][C:13]([OH:15])=O)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:16][C:17]1([CH3:24])[NH:21][C:20](=[O:22])[CH:19]([CH3:23])[NH:18]1>>[CH2:1]([O:8][C:9]([NH:11][CH2:12][C:13]([N:18]1[CH:19]([CH3:23])[C:20](=[O:22])[NH:21][C:17]1([CH3:24])[CH3:16])=[O:15])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 14349BenzyloxycarbonylglycineHCID 13443912HCID 13443912, compound

Product 1

HCID 20163746HCID 20163746, compound

Procedure

The same procedure of the Example 2, starting from N-benzyloxycarbonylglycine and 2,2,5-trimethyl-4-imidazolidinone (m.p. 74°-75° C.; obtained from DL-alaninamide and acetone), afforded 1-(2-benzyloxycarbonylaminoacetyl)-2,2,5-trimethyl-4-imidazolidinone, m.p 170°-171° C., then the title compound m.p. 161°-163° C. dec. Mass spectrum (C.I., i--C4H10, 70 eV, 1.5 mA), m/z=186 (MH+).

Sources & evidence

ORD record
ord-bf83f67b234f450985f73dc33b8921cc
Source dataset
uspto-grants-1987_10
Patent number
US04703054

Reaction notes

Loading…