Methanone, 2-benzofuranylphenyl- → HCID 13728724, compound

HRID 256408Notes

Reaction equation

HRID 256408 reaction equation
[C:1]([C:9]1[O:13][C:12]2[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=2[CH:10]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)(=O)C.[Pd]>[CH2:1]([CH:9]1[CH2:10][C:11]2[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=2[O:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 95808Methanone, 2-benzofuranylphenyl-

Product 1

HCID 13728724HCID 13728724, compoundYield 92.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

To a solution of 22 g (0.1 mole) of 2-benzoylbenzo(b)furan in 250 ml acetic acid was added 3 g 10% Pd/C catalyst and the mixture hydrogenated at 3 atmospheres pressure, with shaking for 70 hours. The mixture was filtered and the filtrate concentrated in vacuo to obtain 19.4 g (92%) of the desired product.

Workup

  1. filtrationThe mixture was filtered
  2. concentrationthe filtrate concentrated in vacuo

Sources & evidence

ORD record
ord-18d4b4c696db47d2888cd9fbb6e52677
Source dataset
uspto-grants-1987_10
Patent number
US04703052

Reaction notes

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