Water → 1-Ethynyl-4-nitrobenzene

HRID 256454Notes

Reaction equation

HRID 256454 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]#[C:11][Si](C)(C)C)=[CH:6][CH:5]=1)([O-:3])=[O:2].C(=O)([O-])[O-].[K+].[K+].O>CO>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]#[CH:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 962WaterHCID 11430Potassium CarbonateHCID 4296099Trimethyl((4-nitrophenyl)ethynyl)silane

Product 1

HCID 1367521-Ethynyl-4-nitrobenzene

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

4-Nitrophenyltrimethylsilylacetylene is reacted at ambient temperature for 3 hours with 3 g of potassium carbonate in 300 ml of methanol. The resulting reaction product mixture is poured into 1500 ml of distilled water to precipitate crude 4-nitrophenylacetylene product. The crude product is separated by filtration, washed with water, and dried in a vacuum oven at 50° C. and 1 Torr.

Workup

  1. customThe resulting reaction product mixture
  2. customto precipitate crude 4-nitrophenylacetylene product
  3. customThe crude product is separated by filtration
  4. washwashed with water
  5. customdried in a vacuum oven at 50° C.

Sources & evidence

ORD record
ord-be020a147dfe44a2a806b41e3bfb2208
Source dataset
uspto-grants-1987_10
Patent number
US04703096

Reaction notes

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