HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 178509021, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 178517766 | HCID 178517766 | — |
| Product | HCID 178509021 | HCID 178509021 | — |
Reaction Steps
A process for the preparation of 5-fluorocytosine comprising reacting 2,5-difluoro-4-chloropyrimidine with a proton acid in the presence of water to yield 2-hydroxy-4-chloro-5-fluoropyrimidine, and reacting the 2-hydroxy-4-chloro-5-fluoropyrimidine with ammonia to yield 5-fluorocytosine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04703121 |
| Source dataset | uspto-grants-1987_10 |
| ORD ID | ord-92d8dab964c24d0a9f9106caae59a01e |
| Source note | uspto-grants-1987_10 |