HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 25648Generated: October 30, 2026
Sodium Iodide → HCID 178484794, compound
https://huagongshe.com/reaction/25648
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | HCID 178484793 | HCID 178484793 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 178484794 | HCID 178484794 | 109% |
Reaction Steps
A solution of 250 mg (0.59 mmol) of trans-N-[4-(5-Chloro-pent-1-ynyl)-cyclohexyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide in 10 ml butan-2-one was treated with 136 mg of NaI (0.91 mmol) and heated at 80° C. for 48 h. Evaporation gave 330 mg of crude trans-N-[4-(5-Iodo-pent-1-ynyl)-cyclohexyl]-N-methyl-4-trifluoromethyl-benzenesulfonamide which was used directly for the next step, MS: 514 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06858651B2 |
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| Source dataset | uspto-grants-2005_02 |
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| ORD ID | ord-5d0e1402790d4588a1e47b2ed450d3e3 |
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| Source note | uspto-grants-2005_02 |
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