HRID256511

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

HCID6029

Uridine

C9H12N2O6

结构：Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1

HCID6175

Cytidine

C9H13N3O5

结构：Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

HCID60961

Adenosine

C10H13N5O4

HCID516951

Monobasic potassium phosphate

H2KO4P

结构：Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

HCID135398635

Guanosine

C10H13N5O5

HCID178418936

未命名化合物

HCID178513825

未命名化合物

结构：OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O

HCID178521066

未命名化合物

PRODUCTS

生成物

结构：NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1

HCID37542

Ribavirin

C8H12N4O5

PROCEDURE

实验过程

By using a substrate solution (pH 6.0) containing 40 mM 1, 2, 4-triazole-3-carboxamide (hereinafter called "triazole") as the base donor, 40 mM uridine, inosine, cytidine, adenosine or guanosine as the saccharide residue donor and 40 mM potassium dihydrogenphosphate, ribavirin was produced in the same manner as in Example 1. The results are shown in Table 7.