反应详情

温度

145 °C

A 500 ml one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen inlet-outlet was charged with 22.52 g (0.75 moles) lactic acid, 47.46 g (0.98 moles) decyl alcohol, 3 ml sulfuric acid and 220 mL toluene. The mixture was heated to 145° C. for 20 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Decyl lactate was distilled under high vacuum to yield 24.03 g (12.4% yield) of clear colorless liquid. According to GC the product is 97.78% pure.

1. customwater was collected as the reaction
2. washby washing three times with 50 ml saturated sodium bicarbonate solution
3. customThe organic layer was collected
4. dry with materialdried over magnesium sulfate
5. distillationDecyl lactate was distilled under high vacuum