Potassium Carbonate → HCID 19784279, compound

HRID 256828Notes

Reaction equation

HRID 256828 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][N:17]3[C:21]4[CH:22]=[CH:23][C:24]([C:26]([F:29])([F:28])[F:27])=[CH:25][C:20]=4[S:19][C:18]3=[N:30]C(=O)C(F)(F)F)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+]>CO>[NH:30]=[C:18]1[N:17]([CH2:16][CH2:15][N:12]2[CH2:11][CH2:10][N:9]([C:6]3[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=3)[CH2:14][CH2:13]2)[C:21]2[CH:22]=[CH:23][C:24]([C:26]([F:27])([F:29])[F:28])=[CH:25][C:20]=2[S:19]1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 19784252HCID 19784252, compound

Product 1

HCID 19784279HCID 19784279, compoundYield 115.9%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using the procedure described in Example 19, but starting with 3-{2-[4-(4-methoxyphenyl)-1-piperazinyl]ethyl}-2-trifluoroacetylimino-6-trifluoromethylbenzothiazoline (0.1 g), a 7% strength aqueous solution (0.5 cc) of potassium carbonate and methanol (5 cc). 2-imino-3-{2-[4-(4-methoxyphenyl)-1-piperazinyl]ethyl}-6-trifluoromethylbenzothiazoline (0.095 g) m.p. 270° C. is obtained.

Sources & evidence

ORD record
ord-de73d8fe24b34edeb8b91bb6f4ef18ec
Source dataset
uspto-grants-1993_11
Patent number
US05260297

Reaction notes

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