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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 256838Generated: October 26, 2026

2-Bromobenzo(b)thiophene → rac-[2-(Benzo[b]thiophen-2-yl)ethynyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol

https://huagongshe.com/reaction/256838

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromobenzo(b)thiopheneHCID 94786—
Reactantrac-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6olHCID 14478563—
Productrac-[2-(Benzo[b]thiophen-2-yl)ethynyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-olHCID 15171820—

Reaction Steps

Reaction of rac-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol with 2-bromobenzo[b]thiophene under the conditions described in example 16 gave after chromatographic isolation and crystallization from ether/hexane colorless crystals with m.p. 120°-123° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05260294
Source datasetuspto-grants-1993_11
ORD IDord-a617309efa024efc821d88d8188e17b2
Source noteuspto-grants-1993_11